Normal Human Kidney Podocytes
人腎足細胞
Normal Human Kidney Podocytes (NhKP) are terminally differentiated cells found lining the outer surface of the glomerular capillaries.
The NhKP are obtained after cortex digestion, and single glomerular isolation. Glomeruli are further digested and then NhKP are isolated by nephrin and podocin positive selection as a pure population, then cryopreserved.
The podocytes have foot processes, that form the slit diaphragm to allow ultrafiltration of the blood based on size and charge and allows the filtration of…, electrolytes, and small and midsized solutes while restricting the passage of anionic molecules and macromolecules.
Expression of slit diaphragm molecules nephrin and podocin will be tested by immunostaining and qPCR. Absence of CD-31 and PDGFβ-R (endothelia and mesangial markers, respectively) will be assessed by immunofluorescence and qPCR.
Podocytes cannot be cultured for more than 1 or 2 passage without loss of their particular traits (like foot processes and expression of slit diaphragm proteins).
THESE PRODUCTS ARE FOR RESEARCH USE ONLY and NOT approved for use in humans or clinical diagnostic testing.
Normal Human Kidney Podocytes
人腎足細胞
PBMC分離試劑盒
人外周血單個核細胞分離試劑盒PBMC分離液
人PBMC分離試劑盒 人PBMC分離液
猴外周血單個核細胞分離試劑盒PBMC分離液
猴PBMC分離試劑盒 猴PBMC分離液
比格犬外周血單個核細胞分離試劑盒PBMC分離液
比格犬PBMC分離試劑盒 比格犬PBMC分離液
狗外周血單個核細胞分離試劑盒PBMC分離液
狗PBMC分離試劑盒 狗PBMC分離液
大鼠外周血單個核細胞分離試劑盒PBMC分離液
大鼠PBMC分離試劑盒 大鼠PBMC分離液
小鼠外周血單個核細胞分離試劑盒PBMC分離液
小鼠PBMC分離試劑盒 小鼠PBMC分離液
兔外周血單個核細胞分離試劑盒PBMC分離液
兔PBMC分離試劑盒 兔PBMC分離液
豬外周血單個核細胞分離試劑盒PBMC分離液
豬PBMC分離試劑盒 豬PBMC分離液
豚鼠外周血單個核細胞分離試劑盒PBMC分離液
豚鼠PBMC分離試劑盒 豚鼠PBMC分離液
骨髓單個核細胞分離試劑盒Bone Marrow Mononuclear Cells Isolation Kit
脾單個核細胞分離試劑盒 Spleen Mononuclear Cells Isolation Kit
紅細胞分離試劑盒
人紅細胞分離試劑盒 紅細胞分離液
猴紅細胞分離試劑盒 紅細胞分離液
比格犬紅細胞分離試劑盒 紅細胞分離液
大鼠紅細胞分離試劑盒 紅細胞分離液
小鼠紅細胞分離試劑盒 紅細胞分離液
ADME相關產品
Ⅰ相代謝穩(wěn)定性試劑盒
Ⅱ相代謝穩(wěn)定性試劑盒
CYP450 酶代謝表型研究試劑盒(化學抑制法/7種抑制劑)
CYP450 酶代謝表型研究試劑盒(重組酶法/7種酶)
CYP450 酶代謝表型研究試劑盒(重組酶法/單酶)
酶抑制(IC50)研究試劑盒(7種特異性底物)
酶抑制(IC50)研究試劑盒(單個酶)
NADPH再生系統(tǒng)
UGT孵育系統(tǒng)
0.1M PBS
肝微粒體(人,猴,犬,大鼠,小鼠)
肝S9(人,猴,犬,大鼠,小鼠)
肝原代細胞(人,猴,犬,大鼠,小鼠)
CYP450(CYP1A2,CYP2A6,CYP2B6,CYP2C8,CYP2C9,CYP2C19,CYP2D6,CYP2E1,CYP3A4)
UGT酶
探針底物,代謝產物,抑制劑(CYP1A2,CYP2A6,CYP2B6,CYP2C8,CYP2C9,CYP2C19,CYP2D6,CYP2E1,CYP3A4)
ADME服務項目
肝微粒體代謝穩(wěn)定性(人,猴,犬,大鼠,小鼠)
肝細胞代謝穩(wěn)定性試驗(人,猴,犬,大鼠,小鼠)
代謝表型研究
代謝產物鑒定
代謝途徑鑒定
種屬比較研究
CYPP450抑制實驗(CYP1A2,CYP2A6,CYP2C9,CYP2C19,CYP2D6,CYP2E1,CYP3A4)
CYPP450誘導實驗
血漿蛋白結合率測定
血漿穩(wěn)定性試驗
跨膜轉運試驗
藥物-藥物相互作用
毒理學研究
Innovative Reagents for Innovative Research
匯智和源致力于為創(chuàng)新藥企業(yè)及生命科學研究機構提供高品質的生物試劑。